Finding a credible target takes months — before a single molecule is tested
Without manually cross-referencing Open Targets, ChEMBL, and PubMed one by one. The platform scores 108,000 target-disease associations and stress-tests every hit against contradicting evidence — so you start with confidence, not hope.
“Find validated targets for non-small cell lung cancer with strong clinical evidence.”
How it works
Name the disease
Type a disease name or EFO ID. The platform queries 108,000 pre-scored omics associations — genetics, expression, and druggability — and returns ranked targets.
Adversarial validation
Each target is stress-tested against clinical trials, ChEMBL bioactivity, and literature. Failed trials and contradicting evidence surface before you commit compute credits.
Dockable targets, ready
You receive ranked targets with suggested PDB IDs, key variants, pathways, and tractability assessments — ready to feed into lead optimization or docking.
Proof
108,436 target-disease associations in omics_targets (Cosmos DB). Composite score: genetics 0.40 + expression 0.30 + druggability 0.30.
56 pharmacogene documents in omics_pgx. 134,940 ClinVar pathogenic variants in omics_resistance.
validate_target stress-tests each hit with tiered weighting: clinical trials (3×), ChEMBL bioactivity (2×), literature (1×), omics (1×).
Start with the right target
108,000 associations. Ranked in seconds. Sign up and run your first query.